Colon cancer

2022 - 12 - 22

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Cedar Rapids runner raises money for colon cancer awareness ... (KCRG)

Cedar Rapids runner Phil Decker started a new colon cancer campaign titled “Tell 5 Friends.”

“Our goal from the beginning of that was just to save one life. He wouldn’t take no for an answer, finishing the Boston Marathon, but he wasn’t done yet. “A big goal of ours is to make sure the people that are over 45 get their colonoscopy, or anybody that has symptoms goes and gets a colonoscopy,” Decker said.

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Cedar Rapids runner raises money to raise awareness for colon ... (NNN)

Cedar Rapids runner raises money to raise awareness for colon cancer and completes 12th round of chemotherapy CEDAR RAPIDS, Iowa (KCRG) - Phil Decker, 45, ...

[](https://nnn.ng/#:~:text=pr blogger outreach) “Our goal from the beginning was just to save one life. [](https://nnn.ng/hausa/#=hausa legit ng) [](https://nnn.ng/i/#=ur shortner) “A big goal of ours is to make sure that people over the age of 45 get a colonoscopy, or anyone who has symptoms gets a colonoscopy,” Decker said. He wouldn’t take no for an answer, finish the Boston Marathon, but he wasn’t done yet. [General news](https://nnn.ng/general-news/)

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Cedar Rapids runner raises money to raise awareness for colon ... (NNN)

Cedar Rapids runner raises money to raise awareness for colon cancer and completes 12th round of chemotherapy CEDAR RAPIDIowa (KCRG) – Phil Decker, 45, ...

[](https://nnn.ng/#:~:text=best blogger outreach companies) [](https://nnn.ng/hausa/#=rariya hausa) [](https://nnn.ng/i/#=shortner link google) Credit: https://nnn.ng/cedar-rapids-runner-raises-money-to-raise-awareness-for-colon-cancer-and-completes-12th-round-of-chemotherapy/ https://nnn.ng/naira-black-market-exchange-rate-today/ “Our goal from the beginning was just to save one life. He wouldn’t take no for an answer, finish the Boston Marathon, but he wasn’t done yet.

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Peteru comedian: Phil Decker runner raises money for colon cancer ... (Vanguard)

Phil Decker, 45, of Cedar Rapids is raising funds to advance more awareness for colon cancer.

A website (tell5friends.org) has been set up for the public to learn more about colon cancer awareness. “Our goal from the beginning of that was just to save one life. He wouldn’t take no for an answer, finishing the Boston Marathon, but he wasn’t done yet.

Freenome CEO Mike Nolan talks colorectal cancer test, clinical trials (MedTech Dive)

The San Francisco-based company recently enrolled a clinical trial for its blood-based cancer test but faces competition in the market for minimally ...

It is that urgent, and so they really have leaned in, and it's a strong sign of support for patients in the U.S. And then there are rivals in the category, and we encourage it. That's because of the fact that the third-party payers, the governmental payers, the policymakers and leaders are really stepping in to do a lot to help make this accessible without that financial burden. We think we'll be in that same [range], around $500 reimbursement, but our view is that the vast majority of patients won't have to pay anything. During the pandemic, people were reluctant to have a screening colonoscopy out of concern potentially of contracting COVID [during the procedure], so they put it off. The FDA approval helps us in that it allows us to be in a better position to be able to be accepted in the guidelines, in particular, the U.S. So when we go to the FDA, we're not a homogenous set of data. And to participate in the study you have to have a screening colonoscopy, that's the anchor in the whole protocol. And so now we're taking those next steps forward to advance in our work to get that to the front lines of clinical care. Because in our trial, we've been very devoted from the get-go [to] doing all that we can to address these issues that exist with regard to health equity and accessibility. Because if you're having a clinical study, say, you live in this ZIP code, but would you travel to another ZIP code in order to participate in a study? In our clinical trial, we pushed ourselves to say, How do we get into not just the communities, but the neighborhoods, really, to understand this concept of trust?

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Image courtesy of "Cancer Network"

Effectiveness, Toxicity, and Survival Predictors of Regorafenib in ... (Cancer Network)

Alberto Calvo-García, PharmG, and colleagues analyzed routinely-collected data to assess regorafenib in metastatic colorectal cancer.

The correlations of ECOG PS (HR, 2.901; 95% CI, 1.195-7.040; P =.019) and LTBS (HR, 1.582; 95% CI, 1.050-2-382; P = .028) to OS were statistically significant. This study protocol was reviewed and approved by the Institutional Review Board (IRB) of La Princesa University Hospital. This study population had as many or more patients than many other retrospective studies14-17 but fewer than the studies led by Yamaguchi and Adenis.18,19 Almost half the patients in our study received regorafenib after 2 previous lines of treatment for metastatic disease, whereas the other half received it after 3 or more previous lines of therapy for metastatic disease. The Kaplan-Meier curves showed that median OS was higher in the LTBS-low group than in the LTBS-med and LTBS-high groups, at 10.77 months (95% CI, 3.42-18.12) vs 6.77 months (95% CI, 2.25-11.29) vs 4.87 months (95% CI, 1.96-7.77; P = .003) respectively. A similar difference between patients with and without liver metastasis was also observed in median PFS, at 3.67 months (95% CI, 3.08-4.25) vs 2.70 months (95% CI, 2.36-3.04), respectively (P = .019; Figure 2C). PFS in those with ECOG PS 0 or 1 was 2.9 months (95% CI, 2.66-3.14) vs 2.5 months (95% CI, 1.81-3.19) in those with ECOG PS 2 or 3 (P = .282; Figure 2A). Regorafenib treatment was discontinued in 30 patients (33.3%) and was interrupted in 29 (32.2%) due to drug-related AEs. The main efficacy variables were OS (defined as the length of time from the initial administration of regorafenib until the last control performed before the study ended or patient death) and PFS (defined as the time between the beginning of treatment and clinical or radiological disease progression). The median time of treatment was 2.8 (range, 1.0-2.8) months. Fifty-two patients (57.8%) were male, and 57 (63.3%) had an ECOG performance status (PS) of 0 to 1. Effectiveness was evaluated by overall survival (OS) and progression-free survival (PFS) using the Kaplan-Meier method. The most frequent were fatigue in 66 patients (73.3%), followed by palmar-plantar erythrodysesthesia in 40 (44.4%).

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Pele's colon cancer worsens; all you want to know about colorectal ... (Hindustan Times)

Football legend Pele's colon cancer has worsened and he may have to spend Christmas in hospital. Here's all you want to know about colon cancer.

He says people with a family history of colon cancer should also consider screening sooner. In this therapy, lab-created antibodies are used to target cancer cells or cells that help cancer cells grow. "In Colonoscopy, a long, flexible and slender tube attached to a video camera is used to view the entire colon and rectum. "Colon cancer is a type of cancer that occurs in your colon (large intestine) or rectum. Radiation therapy directed at the abdomen to treat previous cancers may raise the risk of colon cancer," says the expert. - Radiofrequency ablation: In this procedure, heat is used to destroy cancer cells. Then healthy colon sections are reconnected in a procedure called anastomosis. If colon cancer is detected in early stages, it can be effectively cured. "Some gene mutations passed through generations of your family can raise colon cancer risk significantly. Colon and rectum are the organs that comprise the lower section of your digestive system. Colon cancer is also known as colorectal cancer," says Dr Sunny Jain, HOD and Sr. [Pele'](https://www.hindustantimes.com/sports/football/peles-health-improves-but-he-remains-in-hospital-101670898355625.html)s cancer has worsened and he might have to extend his stay in Albert Einstein hospital over [Christmas](https://www.hindustantimes.com/lifestyle/fashion/christmas-beauty-hacks-5-easy-make-up-hacks-you-must-try-this-festive-season-101671710895927.html) as he is under elevated care related to kidney and heart complications.

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Frontline Trifluridine and Tipiracil Plus Bevacizumab Matches ... (Cancer Network)

The findings, according to a third-party expert, suggest there's no benefit to the use of trifluridine and tipiracil alone in earlier lines of therapy for ...

Trifluridine-tipiracil plus bevacizumab versus capecitabine plus bevacizumab as first-line treatment for patients with metastatic colorectal cancer ineligible for intensive therapy (SOLSTICE): a randomised, open-label phase 3 study. The probability of PFS was estimated as 71% at 6 months in both the trifluridine-tipiracil (95% CI, 66%-75%) and capecitabine (95% CI, 66%-75%) groups. Nine deaths were treatment related, 5 in the experimental group and 4 in the control group. For the study, investigators randomly assigned 856 patients, a slim majority (54%) of whom were male, to receive trifluridine-tipiracil (n = 426) or capecitabine (n = 430) plus bevacizumab between March 21, 2019, and Sept. Patients in the control group received oral capecitabine at a starting dose of either 1000 mg/m² or 1250 mg/m² twice daily on days 1-14 of each 21-day cycle, plus intravenous bevacizumab at 7.5 mg/kg on day 1. There was also no significant difference in the investigator-assessed disease control rates, which were 86% (95% CI, 83%-90%) and 85% (95% CI, 81%-88%), respectively (P = .6256). This continues to consolidate the role of trifluridine-tipiracil, along with regorafenib [Stivarga] and possibly fruquintinib, pending regulatory approval, in patients who fail at least 2 lines of therapy.” The hazard ratio for progression-free survival (PFS) with bevacizumab plus trifluridine-tipiracil vs capecitabine was 0.87 (95% CI, 0.75-1.02; P = .0464), which failed to meet the predetermined significance level (P = .021). doi:10.1016/S2468-1253(22)00334-X The median age of this intention-to-treat population was 73 years (range 22–93; interquartile range [IQR] 65-80). If patients received the lower dose, their dosage could be increased to 1250 mg/m² in subsequent cycles. A prespecified sensitivity analysis by blinded independent central review largely correlated the results of the primary analysis.

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82-Year-Old Brazilian Soccer Great Pelé Hospitalized With Colon ... (Black Enterprise)

The health of soccer icon Pelé is worsening, according to Albert Einstein Jewish Hospital in São Paulo, Brazil, where he is hospitalized.

She [posted](https://www.instagram.com/p/CmcPP-0JIYC/) the news on her Instagram account Wednesday. Last September the beloved soccer legend, who won three World Cups with Brazil, had surgery to remove a tumor. Doctors who are [treating](https://www.blackenterprise.com/reports-of-soccer-legend-pele-being-transferred-to-palliative-care-in-sao-paulo-are-false/) Pelé have released a statement that was posted to his Instagram account [reassuring](https://www.instagram.com/p/CluFX8JOAwl/) fans that he is “still undergoing treatment and the state of [his] health remains stable.” “We, as always, thank you for all the love you show us here in Brazil as well as around the world! “Insta family, our Christmas at home has been suspended. The 82-year-old soccer great was admitted to the hospital Nov.

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Pele to spend Christmas in hospital as cancer advances (Yahoo News)

Brazil football legend Pele's cancer has advanced and he now requires treatment for heart and kidney trouble, according to a medical report released on ...

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The importance of colorectal cancer screenings, especially for ... (WATE 6 On Your Side)

Colorectal cancer disproportionately affects the Black community. According to the American Cancer Society, African Americans are about 20% more likely to get ...

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Pele to remain in hospital through Christmas as colon cancer worsens (THE WEEK)

The health condition of Pele, football king and a major symbol of the sport, has worsened, reported Sao Paulo's Albert Einstein Hospital on Wednesday.

"Thank you for all the love you show us here in Brazil as well as around the world. Heart and kidney failure increase the risk of mortality in elderly patients, according to the Mayo Clinic. On December 1, Pele posted a picture of the moving tribute to him in Qatar on his Facebook page with a note saying, "Friends, I am at the hospital making my monthly visit. Sao Paulo’s Albert Einstein Israelite Hospital is Latin America’s top hospital and among the best in the world. The post came immediately after the hospital statement which noted that Pele would not be transferred to palliative care as was reported by Folha of Sao Paulo earlier in the month. The announcement brought anguish to his fans who had been hoping to see him home for Christmas, as it was confirmed he would remain in the hospital.

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Trifluridine-tipiracil plus bevacizumab 'feasible alternative' for ... (Healio)

“However, some patients with metastatic colorectal cancer might not be candidates for intensive full-dose doublet or triplet first-line chemotherapy for ...

“The safety profile differed between treatments, with more neutropenia with trifluridine-tipiracil plus bevacizumab and more hand-foot syndrome with capecitabine plus bevacizumab, but there were no new safety concerns.” After a median follow-up of 16.6 months, the HR for progression-free survival with trifluridine-tipiracil plus bevacizumab compared with capecitabine plus bevacizumab was 0.87 (95% CI, 0.75-1.02). Patients were randomized to receive trifluridine-tipiracil plus bevacizumab (n = 426) or capecitabine plus bevacizumab (n = 430). < 1%), anemia (14% vs. The estimated probability of progression-free survival was 71% among both treatment groups at 6 months, 39% (95% CI, 34-43) vs. 1%), decreased neutrophil count (18% vs.

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Pele's colon cancer worsens; Everything you want to know about ... (NNN)

– Colectomy with permanent colostomy: In this, surgeons remove the section of your colon that contains a tumor. In this surgery, however, healthy sections of ...

Jain says that to detect this disease at an early stage, people over the age of 45 are recommended to get screened for colon cancer. He says that people with a family history of colon cancer should also consider screening earlier. In this therapy, antibodies made in the laboratory are used to attack cancer cells or cells that help cancer cells grow. During this surgery, surgeons remove the section of the colon that has the tumor and some surrounding healthy tissue. “Colon cancer is a type of cancer that occurs in the colon (large intestine) or rectum. The healthy sections of the colon are then reconnected in a procedure called an anastomosis. The most commonly seen inherited syndromes that increase the risk of colon cancer are familial adenomatous polyposis ( “In colonoscopy, a long, flexible, thin tube attached to a video camera is used to view the entire colon and rectum. If left unidentified or untreated, the cancer can lead to colon obstruction, intestinal obstruction, and spread to other tissues and organs of the body,” says Jain Dr. “Many people with colon cancer do not show symptoms in the early stages of the disease. Colon cancer is also known as colon cancer. The colon and rectum are the organs that make up the lower section of your digestive system.

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Pele health update issued as doctors say Brazil legend's cancer ... (Mirror.co.uk)

Brazil legend Pele is being treated as he battles colon cancer and an update on his condition has been released as he prepares to spend Christmas in ...

He remains in a regular room, is conscious and with stable vital signs." However, his daughters quickly moved to rubbish those reports and said he was still supporting Brazil despite being "sick". The 82-year-old is continuing to battle colon cancer and was hospitalised in Sao Paulo on November 29.

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Cedar Rapids runner raises money to raise awareness for colon ... (NNN)

Cedar Rapids runner raises money to raise awareness for colon cancer and completes 12th round of chemotherapy CEDAR RAPID Iowa KCRG Phil Decker 45 Cedar ...

[](https://nnn.ng/#:~:text=blogger outreach cheap) https://nnn.ng/naira-black-market-exchange-rate-today/ Credit: https://nnn.ng/cedar-rapids-runner-raises-money-to-raise-awareness-for-colon-cancer-and-completes-12th-round-of-chemotherapy/ “Our goal from the beginning was just to save one life. He wouldn’t take no for an answer, finish the Boston Marathon, but he wasn’t done yet. “A big goal of ours is to make sure that people over the age of 45 get a colonoscopy, or anyone who has symptoms gets a colonoscopy,” Decker said.

High levels of ammonia in colon tumors inhibits T cell growth and ... (Newswise)

High levels of ammonia in tumors leads to fewer T cells and immunotherapy resistance in mouse models of colorectal cancer, new findings from the University ...

Crohn’s and Colitis Foundation Research fellowship award (623914) and the American Heart Association postdoctoral fellowship (19POST34380588). “Our work demonstrates that tumors have lost the ability to detoxify ammonia leading to build up,” said Shah. Further, the accumulation of ammonia is likely not isolated to just colorectal tumors. “Now, we have a mechanism that could explain this resistance in tumors beyond colon cancer.” This new method provides a potentially direct avenue to treat tumors and reactivate the immune system.” American Physiological Society postdoctoral fellowship (032650). How does ammonia accumulate in colorectal tumors in the first place? Researchers found that ammonia inhibits the growth and function of T cells, which are vital for anti-tumor immunity. Davenport Collegiate Professor of Physiology and first author of the study. “Our study shows that this is a relatively safe and FDA-approved method that could work alongside immunotherapy to make treatment more effective for patients. “Most colorectal cancers are insensitive to immune therapies,” adds Yatrik Shah, Ph.D., Horace W. “Use of this drug also synergizes with immunotherapy.

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