Cystic fibrosis

2022 - 9 - 21

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Image courtesy of "Cystic Fibrosis News Today"

CF Patients May Respond Well to Coxsackie B Vaccine: Study (Cystic Fibrosis News Today)

Cystic fibrosis patients can get infected with Coxsackie B viruses, but results of mouse models show getting vaccinated may prevent illness.

Unvaccinated mice showed signs of damage in the pancreas, lungs, and liver, which were not found or were lower in vaccinated mice. After receiving both doses, anti-CVB3 antibody levels were similar in the CF mice compared with mice without CF. “This study shows that CVB infections are common in the CF population and we provide preclinical evidence that CVB infections are preventable through vaccination. The mice were given two injections of the vaccine, two weeks apart. “Whether CVB infections are common in CF has not been studied. On average, the CF patients were seropositive for 2.1 types of CVBs, while controls were positive for 2.8 types.

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Image courtesy of "Cystic Fibrosis News Today"

What Is Survivor's Guilt and How Do We Process It? | Cystic... (Cystic Fibrosis News Today)

The death of a classmate causes unfamiliar emotions for columnist William Ryan, prompting the question, what is survivor's guilt?

Last year, I was in the hospital for pneumonia and was being transferred to another hospital. He was planning to go to Virginia Tech and follow in his uncle’s footsteps as a sports broadcaster. He was one of the best people I knew.” [Cystic Fibrosis News Today](https://cysticfibrosisnewstoday.com/) is strictly a news and information website about the disease. At the time, the school had a senior retreat four times a year that groups of about 40 students could go on, and he and I went on the first one together that year. I’m the one who had the Our school, while not as large as a typical public high school in the city, was big for a private school. Upon learning of his death, I was incredibly saddened, yet numb from crying. We had classes together over the years and were on the school’s campus ministry team, the equivalent to a public school’s peer leadership group. When it happened, I was sitting at my computer in the living room, listening to music and doing homework. I was 18 when survivor’s guilt first appeared in my life, and it’ll probably never leave me for as long as I live. I think it’s ultimately a selfish feeling, but sometimes we all have selfish feelings we can’t shake.

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Image courtesy of "Phys.Org"

New study explains mechanisms of salt transport and could help ... (Phys.Org)

In a recently published research article, Pablo Artigas, Ph.D., from the Center for Membrane Protein Research at the Texas Tech University Health Sciences ...

We can do it one way, but we are now trying to do it the other way: come from the Na+/K+ pump to the (non-gastric) H+/K+ pump." "We will use the current and future structures of the non-gastric H+/K+pump to attempt generating specific inhibitors to help treat cystic fibrosis patients." The non-gastric H+/K+ pump participates in K+ reabsorption and contributes to acidification of the airway, an important part of cystic fibrosis pathology. The gastric H+/K+ pump acidifies the stomach and is the target of omeprazole, an antacid drug. In every human cell, the Na+/K+ pump transports two potassium (K+) ions into the cell and brings out three sodium (Na+) ions. The study, "Structure and Function of H+/K+ Pump Mutants Reveal Na+/K+ Pump Mechanisms," was published in September by Nature Communications.

Research explains mechanisms of salt transport and could help treat ... (Mirage News)

In a recently published research article, Pablo Artigas, Ph.D., from the Center for Membrane Protein Research at the Texas Tech University Health.

We can do it one way, but we are now trying to do it the other way: come from the Na+/K+ pump to the (non-gastric) H+/K+ pump.” “We will use the current and future structures of the non-gastric H+/K+pump to attempt generating specific inhibitors to help treat cystic fibrosis patients.” The non-gastric H+/K+ pump participates in K+ reabsorption and contributes to acidification of the airway, an important part of cystic fibrosis pathology. The gastric H+/K+ pump acidifies the stomach and is the target of omeprazole, an antacid drug. The four types of Na+/K+ pumps localize to different tissues. The study, “Structure and Function of H+/K+ Pump Mutants Reveal Na+/K+ Pump Mechanisms,” was published in September by Nature Communications.

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